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Tootekood 25-800-CR

Animal free formulation
Components: Contains 1000 mg/L insulin, human recombinant 550 mg/L transferrin, human recombinant 0.67 mg/L selenious acid

Corning Insulin-Transferrin-Selenium (ITS), 100x, is a growth supplement that should be added at 10
mL/L medium. Supplementation enables a reduction in the FBS requirements of the culture. The components of ITS are required for optimal performance of cells in serum-free or serum-reduced culture.

Insulin is a hormone that promotes glucose and amino acid uptake by the cell. It is thought that the
mitogenic effects of insulin are due to the insulin-like growth factor receptor, IGF-1 receptor.
Transferrin is an iron transport protein that functions to transport iron into the cell. The protein also
serves to detoxify the medium from oxygen radicals and peroxides.2
Selenium is an enzyme cofactor that activates glutathione peroxidase, a player in the detoxification of
oxygen radicals.3

This product is non-returnable. Weight 1 mg

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