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IVISense Pan Cathepsin 750 Fluorescent Probe (ProSense)

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SKU NEV10001EX

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Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.

Revvity’s IVISense™ Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.

IVISense Pan Cathepsin 750 is in our family of “Smart” cathepsin probes, which become fluorescent only after enzymatic cleavage, keeping background down and allowing detection of activated protease. It also offers a secondary wavelength for IVISense Pan Cathepsin, to allow greater flexibility for multiplexing with probes of other excitation/emission wavelengths. 24h imaging at 750 nm.

For research use only. Not for use in diagnostic procedures.

Spetsifikatsioon

Spetsifikatsioon
Product Brand Name

ProSense

Therapeutic Area

Atherosclerosis, Arthritis, Inflammation, Oncology/Cancer

Wavelength

750 nm

Unit Size

1 Vial (10 doses)

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Ettevõttest

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Kaunas, Lithuania

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Phone: +370 (620) 70159

Reg No 305063819

Nova Natura OÜ

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Tallinn, Estonia

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Phone: +37251939223

Reg No 14758203

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