An alternative iMatrix-511 that is xeno-free, recombinant Laminin-511 E8 Fragment expressed in silkworm for promoting adherence and culture of human iPS cells. iMatrix-511 SILK is similar in performance, but lower in cost relative to NP892-011.
iMatrix-511 SILK is a highly purified and refined laminin-511 E8 fragments, produced in Silkworms.
iMatrix-511 SILK features make it an ideal matrix for pluripotent stem cell culture:
- Promotes greater stem cell adhesion than all other matrix proteins that have been tested
- Easy to use (liquid format)
- E8 fragments retain integrin binding specificity and capacity, and display higher potency than natural Laminin-511
- Equivalent performance, but lower cost than the legacy iMatrix-511 product
Laminin is localized to the basement membrane and plays a key role in cell adhesion and proliferation. Laminin-511 (α5, β1 laminin) binds to integrin α6β1 to promote cell signaling. Laminin-511 provides an ideal matrix for the proliferation of a wide variety of cell types including stem and iPS cells.
iMatrix-511 SILK is functionally equivalent to iMatrix-511 (Cat. No. NP892-011). The only difference is the expression system used for bioproduction. The iMatrix-511 SILK product is produced in recombinant silkworm cocoon, while iMatrix-511 is produced in CHO-S cells. Both are E8 fragments that have been purified using the same processes.
Matrixome company name and logo and iMatrix brand name are the property of Matrixome Corp., Japan.
Additional information: https://www.reprocell.com/prod...
A transport cost may apply to this item, it will be specified before shipping.
