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UNCHAINED

Unchained Labs veebiseminarid septembris

sept 02, 2024

3 min

1) "Preventing the danger of unwanted CAR expression during lentivirus production"
Sept 5, 2024, 18:00 (EET)

Join this exclusive webinar to discover advanced strategies for enhancing the quality of lentiviral (LV) vectors in cell therapy manufacturing. This webinar will showcase the Leprechaun platform from Unchained Labs, which promises precise identification and monitoring of CAR expression on the LV surface.

Key takeaways include:

  • Preventing breakthrough expression: Comprehend why preventing breakthrough transgene expression is critical for the safety and efficacy of your cell therapy.
  • Optimizing LV performance: Understand how Lentitek’s system can help prevent unwanted transgene expression.
  • Comprehensive quality monitoring: Learn how Leprechaun helps you monitor breakthrough expression by measuring the titer of LV with transgene protein on the surface straight from harvest.

Register HERE

2) "Addressing the challenge of screening DNA-LNP formulations for targeting the brain"
Sept 12, 2024, 18:00 (EET)

In this webinar, Razieh Karamzadeh will present data from experiments conducted at Karolinska Institute using Unchained Labs’ Sunscreen and Sunshine systems for production of DNA-LNPs for in vitro screening, then scaling-up selected LNPs for in vivo studies.

Key Takeaways:

  • The challenges of targeted delivery of LNPs
  • The key benefit of high-throughput screening for improving extra-hepatic delivery
  • The benefit of consistent particle production at different volume scales

Register HERE


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