Tasuta koolitus - "Assay Guidance Workshop for Cell-Based Assays and Lead Discovery" (16-17. Nov 2021, virtuaalne)
sept 30, 2021
6 min
Assay Guidance Workshop for Cell-Based Assays and Lead Discovery
Tuesday November 16, 2021 – Wednesday November 17, 2021 Virtual (All times are in EEST)
AGENDA: Day 1: High-Content Screening and Analysis
19:30 PM NCATS Assay Guidance Manual: Setting the Standard for Rigor in Translational Science
Sarine Markossian, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH)
19:45 PM The Evolution of HCS Imaging and Impact on Discovery
Joe Trask, PerkinElmer
20:15 PM Assay Development for Imaging Assays: Design, Data Management and Validation
Steven Haney, Valo Health
20:45 PM Introduction to High Content Image Analysis with CellProfiler
Beth Cimini, Broad Institute
21:15 PM Break
21:30 PM Machine Learning and Assay Development
Jonathan Sexton, University of Michigan, Ann Arbor
22:00 PM Transforming Drug Discovery via Image-Based Profiling
Niranj Chandrasekaran, Broad Institute
22:30 PM Break
22:45 PM Functional Genomics: Taking Discovery to the Third Dimension
Kaylene Simpson, Peter MacCallum Cancer Centre
23:15 PM Panel Discussion – Challenges and Applications of HCS
Moderator: Kaylene Simpson, Peter MacCallum Cancer Centre
Panelists: Joe Trask, PerkinElmer; Steven Haney, Valo Health; Beth Cimini, Broad Institute; Jonathan Sexton, University of Michigan, Ann Arbor; David Egan, Core Life Analytics; Niranj Chandrasekaran, Broad Institute
00:00 PM Adjourn
AGENDA: Day 2: Complex In vitro Models (CIVMs) in Drug Discovery
20:00 PM Opening Note
Sarine Markossian, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH)
20:05 PM Drug Screening with Engineered 3D Tissue Models
Marc Ferrer, NCATS, NIH
20:35 PM Organ-Chips: From Potential to Application
Lorna Ewart, Emulate
21:05 PM TBD
Jan Lichtenberg, InSphero AG
21:35 PM Break
21:45 PM Developing Scalable Complex Models for High Throughput Screening
BanuPriya Sridharan, GlaxoSmithKline
22:15 PM Validating Cell Health Assays Applied to 3D Cultures
Terry Riss, Promega Corporation
22:45 PM Break
23:00 PM Applying a Holistic Approach for 3D HCS Imaging Assays
Joe Trask, PerkinElmer
23:30 PM Panel Discussion – Challenges and Applications of CIVMs in Drug Discovery
Moderator: Madhu Lal-Nag, FDA
Panelists: Marc Ferrer, NCATS; Lorna Ewart, Emulate; Jan Lichtenberg, InSphero AG; BanuPriya Sridharan, GlaxoSmithKline; Terry Riss, Promega Corporation; Joe Trask, PerkinElmer
00:15 AM Adjourn
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